▎ 摘 要
NOVELTY - Composite material comprises a graphene-based substrate, with nanoparticles of at least two different metals bonded thereto, where the loading of metal ions is at least 10 % based on the weight of the material. USE - Composite material used as a medicine and microbicide for the treatment of a bacterial infection. The bacterial infection is a topical infection (all claimed). ADVANTAGE - The composite material increases weight, improves content uniformity, enhances or retard the rate of disintegration of the tablet, improves the taste of the tablet, and has excellent chemical and physical properties. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) a process for the preparation of a nanoparticulate material, which involves providing a mixture of graphene oxide and a solution containing salts of at least two different metals; adding a reducing agent to the mixture; (2) a pesticidal composition, which comprises composite material together with suitable excipients and/or adjuvants; and (3) a material, which comprises a microbicidal amount of a composite material.