• 专利标题:   Protective cleaning solution useful for antibacterial sterilizing, comprises e.g. cocamidopropyl betaine, propylene glycol, carbomer, potassium hydroxide, hyaluronic acid, silver ion solution, graphene oxide dispersion solution and water.
  • 专利号:   CN111617103-A
  • 发明人:   WEN J, DUAN L
  • 专利权人:   WEN J
  • 国际专利分类:   A61K033/38, A61K033/44, A61K008/19, A61P031/02, A61Q017/00, A61Q019/10
  • 专利详细信息:   CN111617103-A 04 Sep 2020 A61K-033/38 202076 Pages: 8 Chinese
  • 申请详细信息:   CN111617103-A CN10294609 15 Apr 2020
  • 优先权号:   CN10294609

▎ 摘  要

NOVELTY - Protective cleaning solution comprises 3-5 wt.% cocamidopropyl betaine, 1-3 wt.% glycerol, 1-10 wt.% propylene glycol, 0.1-0.5 wt.% carbomer, 0.1-0.5 wt.% potassium hydroxide, 0.05-0.2 wt.% hyaluronic acid, and silver ion solution, graphene oxide dispersion solution and water (balance). Prepared e.g. by (i) providing 3-5 wt.% cocamidopropyl betaine, 1-3 wt.% glycerol, 0.05-5 wt.% silver ion solution, 0.1-3 wt.% graphene oxide dispersion solution, and 79.9% purified water, heating to 80 degrees C for 40 minutes to obtain mixed solution A, (ii) providing 0.1-0.5 wt.% carbomer, 0.1-0.5 wt.% potassium hydroxide, 1-10 wt.% propylene glycol, adding 20% purified water, heating to 80 degrees C for 40 minutes to obtain mixed solution B, and (iii) vacuumizing the emulsification pot, preserving the vacuum degree at 0.06 Pa, turning on the heating button of the emulsification pot for heating the emulsification pot. USE - The protective cleaning solution is useful for antibacterial sterilizing. ADVANTAGE - The cleaning solution reduces number of bacteria and viruses on the skin at the initial stage of use of the product, integrates washing and protection, makes personal protection function more efficient, safe, mild, and durable, and is worthy for popularization. DETAILED DESCRIPTION - Protective cleaning solution comprises 3-5 wt.% cocamidopropyl betaine, 1-3 wt.% glycerol, 1-10 wt.% propylene glycol, 0.1-0.5 wt.% carbomer, 0.1-0.5 wt.% potassium hydroxide, 0.05-0.2 wt.% hyaluronic acid, and silver ion solution, graphene oxide dispersion solution and water (balance). Prepared by (i) providing 3-5 wt.% cocamidopropyl betaine, 1-3 wt.% glycerol, 0.05-5 wt.% silver ion solution, 0.1-3 wt.% graphene oxide dispersion solution, and 79.9% purified water, heating to 80 degrees C for 40 minutes to obtain mixed solution A, (ii) providing 0.1-0.5 wt.% carbomer, 0.1-0.5 wt.% potassium hydroxide, 1-10 wt.% propylene glycol, adding 20% purified water, heating to 80 degrees C for 40 minutes to obtain mixed solution B, (iii) vacuumizing the emulsification pot, preserving the vacuum degree at 0.06 Pa, turning on the heating button of the emulsification pot for heating the emulsification pot, (iv) slowly pumping the mixed liquid A into emulsifying pot under vacuum condition, and heat preserving at 80 degrees C in constant temperature, (v) slowly pumping the mixed solution B into emulsifying pot with stirring speed of 20 revolutions/minute, heat preserving at 80 degrees C in constant temperature, turning on the homogenizer button, homogenizing and stirring at speed of 10 revolutions/minute for 8 minutes, increasing the speed, and stirring at speed of 25 revolutions/minute for 15 minutes, (vi) turning on the cooling water, controlling the speed of the cooling water, stirring, and cooling the emulsification pot to 60 degrees C in 45 minutes, (vii) slowly adding 0.05-0.2 wt.% hyaluronic acid into the emulsifying pot, turning on the vacuum button, heat preserving at 0.06 Pa, stirring, and cooling the emulsifying pot to 55 degrees C for 15 minutes to obtain mixed solution, and (viii) placing the mixed solution obtained in step (vii) in sterilized container, cooling to 25 degrees C, covering with plastic wrap, and sealing for 24 hours.