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  • 专利标题:   Preparation of organic microbubble complex particles used for ultrasound contrast agent comprises sonicating aqueous solution including graphene compound and amphiphilic material in presence of gas comprising inert gas or carbon dioxide.
  • 专利号:   US2015125399-A1, KR1520443-B1, US9561293-B2
  • 发明人:   CHAR K, PARK S
  • 专利权人:   SNU R DB FOUND, UNIV SEOUL NAT R DB FOUND, SNU R DB FOUND
  • 国际专利分类:   A61K049/22, A61K049/04, A61K049/08, A61K009/16, A61B008/00
  • 专利详细信息:   US2015125399-A1 07 May 2015 A61K-049/22 201532 Pages: 17 English
  • 申请详细信息:   US2015125399-A1 US200189 07 Mar 2014
  • 优先权号:   KR134213

▎ 摘　　要

NOVELTY - Preparation of organic microbubble complex particles comprises sonicating an aqueous solution comprising a graphene compound and an amphiphilic material in the presence of a gas comprising an inert gas or carbon dioxide. USE - Method for preparing organic microbubble complex particles used for an ultrasound contrast agent (claimed). ADVANTAGE - The method can provide organic microbubble complex particles having high uniformity of particle sizes and excellent long term shape stability and storage stability.