▎ 摘　　要

NOVELTY - A beta -lactam antibiotic multi-template molecularly imprinted magnetic composite material is obtained by polymerizing a magnetic carbon-based silica composite material as a carrier, beta -lactam antibiotics as a template molecule, and 3-aminopropyltriethoxysilane as functional monomer in the presence of a crosslinking agent and an initiator, and eluting the template molecule. The composite material includes magnetic carbon-based hybrid material and silicon dioxide coated on the surface of the magnetic carbon-based hybrid material. The hybrid material includes a carbon-based hybrid material, and magnetic particles supported on the carbon-based hybrid material. The carbon-based hybrid material is formed by esterification of graphene oxide and carbon nanotubes with an esterification agent. The antibiotics are cephalexin, cefazolin sodium, penicillin G sodium, oxacillin sodium or amoxicillin. USE - beta -Lactam antibiotic multi-template molecularly imprinted magnetic composite material for separation of beta -lactam antibiotics from water samples (claimed). ADVANTAGE - The composite material has excellent adsorption capacity and workability, and can effectively detect and separate lactam antibiotics in complex environment water sample. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of beta -lactam antibiotic multi-template molecularly imprinted magnetic composite material, which involves esterifying mixture of graphene oxide, carbon nanotubes, esterification agent and solvent (a) to obtain a carbon-based hybrid material, reacting hybrid material, a metal salt, and an alkaline reagent to obtain a magnetic carbon-based hybrid material loaded with magnetic particles, dispersing hybrid material in a mixed solution of ethanol, water and concentrated ammonia, adding ethyl orthosilicate for hydrolysis, magnetically separating, drying to obtain a magnetic carbon-based silica composite material, dissolving lactam antibiotics in an organic solvent (b), adding 3-aminopropyltriethoxysilane, adding crosslinking agent and initiator, removing template molecule with an eluent.