▎ 摘 要
NOVELTY - Detecting infection in urine comprises (i) contacting urine from the subject with a device for detecting an infection, where the device comprises electrochemical sensor array, and (ii) measuring presence, absence or amount of at least one target molecule and/or metabolic activity within the urine sample, where the target molecule and/or the metabolic activity is associated with the infection, where the electrochemical sensor array performs the measuring. USE - The method is useful for: detecting urinary tract infection i.e. catheter associated urinary tract infections (CAUTI) and wound infection, caused by a pathogen e.g. bacterium e.g. Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae, Klebsiella species, Staphylococcus aureus, Enterococcus faecalis, Enterococcus species, Acinetobacter baumannii, Streptococcus group A species and Group B species, Staphylococcus epidermidis, Pseudomonas aeruginosa, Clostridium difficile, or Salmonella enterica, and fungus e.g. Candida albicans, Cryptococcus neoformans, or Aspergillus species, preferably Candida albicans. ADVANTAGE - The method provides device capable of contemporaneously detecting the presence or absence of at least 2-10 pathogens or signals associated with the pathogen, is simple, rapid, cost effective, and require less labor. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for (1) detecting urinary tract infection or wound infection comprising (i) contacting urine or wound exudate with a device for detecting infection, where the device comprises electrochemical sensor array, and (ii) measuring presence, absence or amount of at least one target molecule and/or metabolic activity within the urine sample, where the target molecule and/or the metabolic activity is associated with the infection, where the electrochemical sensor array performs the measuring; and (2) detecting wound infection comprising (i) administering a dressing to a wound, optionally where the dressing comprises oxidized regenerated cellulose (ORC) and/or collagen, (ii) applying negative pressure to the wound, (iii) collecting wound exudate in wound exudate collection container, (iv) contacting wound exudate from wound dressing or wound exudate collection container with device for detecting infection, where the device comprises electrochemical sensor array, and (v) measuring presence, absence or amount of target molecule and/or metabolic activity within the wound exudate, where the target molecule and/or the metabolic activity is associated with the infection, where the electrochemical sensor array performs the measuring.