• 专利标题:   Molecular detection device used to e.g. analyze DNA, comprises electrode array of conducting electrode pairs, and drain electrode, graphene bridge connecting source electrode to drain electrode, and enzyme biomolecule coupled to bridge.
  • 专利号:   WO2021237182-A1
  • 发明人:   JIN S, CHOI C, MOLA P, MERRIMAN B
  • 专利权人:   ROSWELL BIOTECHNOLOGIES INC
  • 国际专利分类:   B01L007/00, C12Q001/6869
  • 专利详细信息:   WO2021237182-A1 25 Nov 2021 202102 Pages: 31 English
  • 申请详细信息:   WO2021237182-A1 WOUS033784 21 May 2021
  • 优先权号:   US028796P, US028914P

▎ 摘  要

NOVELTY - Molecular detection device comprises an electrode array of conducting electrode pairs, each electrode pair having a source electrode and a drain electrode separated by a nanogap, a graphene bridge connecting the source electrode to the drain electrode of an electrode pair to form a field effect transistor, and an enzyme biomolecule coupled to the graphene bridge, where the bridge is shaped to guide and limit the coupling of the biomolecule. USE - The device is useful: as biomolecular sensing and memory storage devices; for analyzing DNA and related biomolecules; and in DNA, RNA or protein sequencing. ADVANTAGE - The device: improves quality and accuracy of sequencing, and time; and avoids using complicated, bulky and expensive fluorescent type labeling apparatus, hence economical. DESCRIPTION OF DRAWING(S) - The figure shows aligned graphene array. Dielectric layer (109) Graphene array (110) Exposed graphene (112)