▎ 摘　　要

NOVELTY - Nano-gold tube composite film coated with graphene oxide comprises hollow tubular nano-gold film layer and a graphene oxide layer. The thickness of the hollow tubular nano-gold film layer is 60-150 nm and the thickness of the graphene oxide layer is 0.6-12 nm. USE - The film is useful for preparing three dimensional flexible Raman enhanced substrate and in Raman enhanced spectrum (claimed). ADVANTAGE - The film has high detection sensitivity, ensures raman enhancement effect, prevents the oxidation of gold nanoparticles, improves stability of the substrate, and solves the shortcomings of the substrate as a Raman-reinforced substrate. DETAILED DESCRIPTION - INDEPENDENT CLAIM ARE also includes for: (1) method for preparing nano-gold tube composite film, comprising (i) dissolving polymer with solvent, stirring for 10-15 hours to obtain spinning solution, (ii) controlling the temperature at 18-25 degrees C, the humidity is 50-60%, the positive voltage of electrospinning is 18-25 KV, the negative voltage is 0 KV, and the spinning distance is 20 cm, the spinning speed is 0.2-0.6 mm/minute, and the spinning solution is directly spun into nanofiber film on the receiving plate, (iii) removing the nanofiber film, and plating the gold nanoparticles on the surface of the nanofiber film by a vacuum evaporation method to obtain gold-plated nanofiber film, (iv) placing the gold-plated nanofiber film in formic acid for 5-10 hours, dissolving and removing the nanofibers, filtering out, and drying at room temperature to obtain hollow tubular nanogold film, (v) adding graphene oxide into deionized water, and ultrasonically dispersing to form a graphene oxide solution, (vi) using liquid droplet coating method to apply graphene oxide solution to surface of the hollow tubular nano-gold film, and drying at room temperature; and (2) three-dimensional flexible Raman enhancement substrate, where the three-dimensional flexible Raman-enhancement substrate is prepared from nano-gold tube composite film.