▎ 摘 要
NOVELTY - Preparing conductive graphite polymer patch involves mixing the pyrrole monomer suspension with the polythiophenes (pTS) dopant solution to obtain a mixture. The oxidant is added to the mixture, allowed to stand for 15-60 minutes, stirred for polymerization, filtered, washed, and dried to obtain polypyrrole. The multi-layer graphene nanosheet is dispersed in distilled water to obtain the graphene solution. The chloroacetic acid powder and sodium hydroxide tablet are added into the graphene solution, stirred until the redundant solid is completely dissolved. The ultrasonic treatment is performed to obtain functional graphene. The functional graphene and heparin powder are dispersed in acetone, and formic acid is added to obtain a functional graphene-heparin composite solution. The polycaprolactone, chitosan, and polypyrrole are mixed to obtain the polycaprolactone/chitosan/polypyrrole blend. USE - Method for preparing conductive graphite polymer patch used as biological medicine material, which guides the cardiomyocyte differentiation to stimulate cardiac tissue repair. ADVANTAGE - The method has biological compatibility, biological degradability, effective elastomer performance, high elongation, where non-toxic polycaprolactone and chitosan blend improves the mechanical property and electric spinnability with polypyrrole to obtain a biodegradable, good conductive performance. DETAILED DESCRIPTION - Preparing conductive graphite polymer patch involves mixing the pyrrole monomer suspension with the polythiophenes dopant solution to obtain a mixture. The oxidant is added to the mixture, allowed to stand for 15-60 minutes, stirred for polymerization, filtered, washed, and dried to obtain polypyrrole. The multi-layer graphene nanosheet is dispersed in distilled water to obtain the graphene solution. The chloroacetic acid powder and sodium hydroxide tablet are added into the graphene solution, stirred until the redundant solid is completely dissolved. The ultrasonic treatment is performed to obtain functional graphene. The functional graphene and heparin powder are dispersed in acetone, and formic acid is added to obtain a functional graphene-heparin composite solution. The polycaprolactone, chitosan, and polypyrrole are mixed to obtain the polycaprolactone/chitosan/polypyrrole blend. The functional graphene-heparin composite solution is mixed and stirred with the polycaprolactone/chitosan/polypyrrole blend to obtain a suspension. The suspension is connected with the injection pump through the injector. The electrostatic spinning reaction is performed to obtain a conductive graphene polymer patch.