▎ 摘　　要

NOVELTY - Nanofiber bilirubin adsorbent is prepared by (i) dissolving polyacrylonitrile, pore former and channel proppant in organic solvent to obtain a mixed solution comprising 4-20 wt.% polyacrylonitrile, 6-40 wt.% pore former and 2-30 wt.% pore proppant, and stirring until clarified and electrospinning to obtain blended nanofibers, (ii) placing the blended nanofibers in a eluent to remove pore former from the fibers, performing elution at 20-80 degrees C for 2-48 hours, and drying the eluted blended nanofibers to obtain nanofibers with penetrating mesoporous channels, and (iii) placing the obtained nanofibers in a polyamine composite solution at 80-200 degrees C under reflux or solvothermal reaction for 1-24 hours, washing, drying to obtain amine-functionalized nanofibers, placing in a halogenated composite solution at 40-200 degrees C reflux or solvothermal reaction for 2-48 hours, washing and drying to obtain the product having multi-action site through which the mesoporous channel is communicated. USE - The adsorbent useful in preparation of medicine for removing excess bilirubin in blood (claimed). ADVANTAGE - The adsorbent quickly, high-capacity, and selectively removes bilirubin, has bilirubin removal rate up to 96.8%, high stability, excellent compatibility and easy realization of industrial production, is prepared by simple and easy preparation method, and recognizes bilirubin molecules using multi-action sites such as electrostatic adsorption, hydrogen bonding and pi pi interaction. The method improves the adsorption capacity and selectivity of the adsorbent, and increases the utilization rate of adsorption sites and accelerates the adsorption rate by the connected mesoporous channels on the fibers.