• 专利标题:   Nitrogen-sulfur-doped graphene quantum dot used for preparing lysine fluorescence detection reagent.
  • 专利号:   CN106883849-A, CN106883849-B
  • 发明人:   CHENG R, GE C, CHEN L, ZHANG L, WANG D
  • 专利权人:   UNIV WENZHOU MEDICAL, UNIV WENZHOU MEDICAL
  • 国际专利分类:   C09K011/65, G01N021/64
  • 专利详细信息:   CN106883849-A 23 Jun 2017 C09K-011/65 201759 Pages: 6 Chinese
  • 申请详细信息:   CN106883849-A CN10195330 29 Mar 2017
  • 优先权号:   CN10195330

▎ 摘  要

NOVELTY - A nitrogen-sulfur-doped graphene quantum dot (I) is claimed. USE - Nitrogen-sulfur-doped graphene quantum dot used for preparing lysine fluorescence detection reagent. ADVANTAGE - The nitrogen-sulfur-doped graphene quantum dot is rich in oxygen-containing functional groups, and has excellent water dispersibility and biocompatibility, and high luminosity and quantum efficiency. The quantum dot preparation method is simple and carried out under mild condition. Lysine has high selectivity and sensitivity, and is detected without being affected by coexisting amino acids and carbohydrate biomolecules such as alanine, proline, glycine, methionine, arginine, leucine, glucose, glucosamine, galactose, sucrose and other substances. DETAILED DESCRIPTION - A nitrogen-sulfur-doped graphene quantum dot of formula (I), is claimed. INDEPENDENT CLAIMS are included for the following: (1) preparation of the nitrogen-sulfur-doped graphene quantum dot, which involves adding 5-35 mL deionized water to citric acid and thiourea, stirring, transferring the mixed solution into a reaction vessel, heating, and dialyzing the obtained product using dialysis bag for three days; and (2) application of the nitrogen-sulfur-doped graphene quantum dot for preparing lysine fluorescence detection reagent.