• 专利标题:   Detecting nitroimidazole antibiotic in honey by e.g. dissolving oxidized graphene in N, N-dimethyl formamide solution, ultrasonically dispersing with ferroferric oxide, and mixing zirconium tetrachloride with suspension, and drying.
  • 专利号:   CN113030309-A, CN113030309-B
  • 发明人:   LI Z, XU Y, QIAN M, WANG J, ZHANG H, JI X, ZHOU M
  • 专利权人:   UNIV ZHEJIANG TECHNOLOGY, ZHEJIANG AGRIC SCI ACAD
  • 国际专利分类:   G01N030/02, G01N030/06, G01N030/72
  • 专利详细信息:   CN113030309-A 25 Jun 2021 G01N-030/02 202163 Pages: 21 Chinese
  • 申请详细信息:   CN113030309-A CN10231499 02 Mar 2021
  • 优先权号:   CN10231499

▎ 摘  要

NOVELTY - Detecting nitroimidazole antibiotic in honey involves (a) ultrasonically dissolving oxidized graphene in N, N-dimethylformamide solution, adding ferroferric oxide, ultrasonically dispersing, mixing zirconium tetrachloride in the suspension, ultrasonically stirring and dispersing, adding 4,4'-phthalic acid, uniformly mixing to obtain mixed solution, heating the mixed solution at 110-176 degrees C for more than 24 hours, washing, separating the synthesized solid from the solution by magnetic separation, drying, and grinding and (b) weighing honey sample, adjusting pH to 3-7, adding metal-organic framework (UiO-67)-graphene oxide-iron oxide powder, performing magnetic solid phase extraction at 500-800 revolutions/minute for adsorption, using magnet to absorb and separate UIO-67-graphene oxide-iron oxide powder, washing the separated UIO-67-graphene oxide-iron oxide powder with water, completely immersing into the eluent, performing desorption and drying the eluent to obtain the processed sample. USE - The method is useful for detecting nitroimidazole antibiotic in honey. ADVANTAGE - The method enables detecting nitroimidazole antibiotic in honey sample in a simple, rapid and accurate manner, and can be widely popularized and applied. DETAILED DESCRIPTION - An independent claim is also included for a method for sample processing by detecting nitroimidazole antibiotics in honey.