▎ 摘　　要

NOVELTY - Synthesizing 3-descarbamoyl cefuroxime acid by using a graphene-supported copper catalyst involves adding furan ammonium salt and 7-aminocephalosporanic acid undergo amidation reaction under the action of the graphene-supported copper catalyst, and then adding lye, occuring hydrolysis reaction, and filtering filtrate. The filtrate is crystallized to obtain 3-decarbamoyl cefuroxime acid. USE - Method for synthesizing 3-descarbamoyl cefuroxime acid by using graphene-supported copper catalyst. ADVANTAGE - The method is greatly shortens the synthesis steps of the target compound, avoids the use of amidation reagents such as phosphorus oxychloride or phosphorus pentachloride, reduces the content of trans-isomer impurities in the target product, and improves the product yield. The catalyst recovery rate is high, which reduces the amount of graphene-supported copper catalyst, and has simple process operation, cost-effective, and reliable safety.