▎ 摘　　要

NOVELTY - Preparing molecularly imprinted composite paste electrode sensor involves forming nano niobium nitride/nano cesium lead bromide/graphene oxide composite paste electrode. The composite paste electrode uses nano niobium nitride, nano cesium lead bromide and graphene oxide as conductive material. The 1-carboxyethyl-3-methylimidazole hydrogen sulfate is used as adhesive, and diethanolamine and ethanol as dispersant. The itaconic acid and 3-aminophenylboronic acid are used as functional monomers, methylene bisacrylamide is used as crosslinking agent, and dimethyl azodiisobutyrate is used as initiator in alkaline environment under the protection of nitrogen. The acyclovir is used as template for cross-linking polymerization to prepare acyclovir molecularly imprinted polymer. The N,N-dimethylformamide and acyclovir molecularly imprinted polymer are mixed and heated to dissolve. USE - Method for preparing molecularly imprinted composite paste electrode sensor for detecting acyclovir. ADVANTAGE - The method has good response performance, good selectivity and high sensitivity, combines the molecular imprinting technology, layer-by-layer self-assembly method and drop coating method. DETAILED DESCRIPTION - Preparing molecularly imprinted composite paste electrode sensor involves forming nano niobium nitride/nano cesium lead bromide/graphene oxide composite paste electrode. The composite paste electrode uses nano niobium nitride, nano cesium lead bromide and graphene oxide as conductive material. The 1-carboxyethyl-3-methylimidazole hydrogen sulfate is used as adhesive, and diethanolamine and ethanol as dispersant. The itaconic acid and 3-aminophenylboronic acid are used as functional monomers, methylene bisacrylamide is used as crosslinking agent, and dimethyl azodiisobutyrate is used as initiator in alkaline environment under the protection of nitrogen. The acyclovir is used as template for cross-linking polymerization to prepare acyclovir molecularly imprinted polymer. The N,N-dimethylformamide and acyclovir molecularly imprinted polymer are mixed and heated to dissolve. The modified solution of acyclovir molecularly imprinted polymer is added dropwise to nano niobium nitride/nano cesium lead bromide/graphene oxide composite paste electrode. The solvent is volatilized. The template molecule is removed by drip coating method to obtain molecularly imprinted composite paste electrode sensor. An INDEPENDENT CLAIM is included for a method for detecting acyclovir, which involves preparing set of acyclovir standard solutions of different concentrations includes blank standard sample which is boric acid-potassium chloride-sodium hydroxide buffer solution of pH of 8.2, using silver/silver chloride as reference electrode, using platinum wire electrode as auxiliary electrode, using molecularly imprinted composite paste electrode sensor as working electrode to form three-electrode system, connecting to electrochemical workstation of K3(Fe(CN)6) in solution, using cyclic voltammetry to detect in the potential range of (-)0.6-1.2 volt, recording response current of the blank standard sample as I0, response current of acyclovir standard solutions containing different concentrations is Ii, and difference in response current reduction is I0-Ii, drawing deltaI-c working curve according to the linear relationship between deltaI and the mass concentration c of acyclovir standard solution, replacing acyclovir standard solution in S1 with the sample to be tested, and performing detection, obtaining content of acyclovir in the sample to be tested according to the difference delta I of the response current reduction and working curve.