▎ 摘　　要

NOVELTY - Biosensor for optical detection of human papilloma virus (HPV) in biological samples comprises (a) functionalized surface, (b) dendrimer, (c) spacer, (d) capture probe, (e) reporter probe, and (f) nanoparticle. USE - The biosensor is useful for: detecting human papilloma virus (HPV) in biological samples. ADVANTAGE - The biosensor is simple, sensitive, selective, cost-effective and provides reproducible results. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for in vitro detection of HPV in a biological sample comprising contacting sample with optical biosensor, where the biosensor comprises functionalized surface, dendrimer, spacer, capture probe, reporter probe, and nanoparticles.