▎ 摘　　要

NOVELTY - Fabrication of graphene-based circuits on a substrate involves: (a) preparing a printable ink comprising graphene or graphene oxide exfoliated from graphite from a bulk synthesis process; and (b) aerosol jet printing a circuit on a substrate using the printable ink. USE - The method is useful for fabrication of graphene-based circuits on a substrate; for electrochemical sensing comprising biosensing; and for at least one of: (a) printable electronic devices; (b) sensors; (c) biosensors; (d) point-of-care diagnostic devices; (e) wearable devices; (f) flexible electronics; (g) micro-electromechanical (MEMs) biosensors; (h) optoelectrical biosensors; (i) thermistor biosensors; and (j) over the counter testing kits (all claimed). ADVANTAGE - Methods and systems are provided fabrication of high resolution, high-throughput electrochemical sensing circuits on a substrate. High resolution electrochemical sensing circuits are printed by an effective additive technique to the substrate. The substrate and printed circuits can be fabricated with additive manufacturing techniques. Because it does not require subtractive manufacturing, the fabrication can be relatively economical.