▎ 摘　　要

NOVELTY - Linker compounds SH-(CH)n-NH2 (I) with carbon number 6 or more, SH-(CH)n-COOH (II), SH-(CH)n-SH (III), (OH)m-(CH)n-COOH (IV) or (OH)m-(CH)n-NH2 (V), where average surface roughness (Ra) of the chip substrate is greater than 250 nm, the coverage of the connector on the chip substrate is 40-80%. USE - Linker suitable for fixing biological probes on chip substrate of sensor, where the biological probe is a biological probe of enzyme, protein, deoxyribonucleic acid and ribonucleic acid or an odontoglossum ringspot virus antibody (claimed). ADVANTAGE - The linker has optimal carbon chain length connectors and coverage for substrates with different roughness, and greatly improves the grasping ability of the electrochemical sensing chip to the detected target. DETAILED DESCRIPTION - Linker compounds of formulae SH-(CH)n-NH2 (I) with carbon number 6 or more, SH-(CH)n-COOH (II), SH-(CH)n-SH (III), (OH)m-(CH)n-COOH (IV) or (OH)m-(CH)n-NH2 (V), where average surface roughness (Ra) of the chip substrate is greater than 250 nm, the coverage of the connector on the chip substrate is 40-80%. where m, n are integers greater than 1.