• 专利标题:   Preparation of hyaluronic acid/graphene/polyacrylamide composite hydrogel used as e.g. artificial skin, mixing hyaluronic acid, graphene oxide solution, acrylamide monomer and initiator solution in container and sealing container.
  • 专利号:   CN106478962-A
  • 发明人:   YU J, CHEN Y, HU Z, WANG Y, ZHU J
  • 专利权人:   UNIV DONGHUA
  • 国际专利分类:   C08F120/56, C08J003/075, C08K003/04, C08K009/00, C08L033/26, C08L005/08
  • 专利详细信息:   CN106478962-A 08 Mar 2017 C08J-003/075 201727 Pages: 9 Chinese
  • 申请详细信息:   CN106478962-A CN10853047 26 Sep 2016
  • 优先权号:   CN10853047

▎ 摘  要

NOVELTY - Preparation of hyaluronic acid/graphene/polyacrylamide composite hydrogel involves adding hyaluronic acid to graphene oxide solution, stirring, adding acrylamide monomer, stirring to obtain hyaluronic acid/graphene/ acrylamide dispersion, adding initiator solution and accelerator and then stirring, soaking in ice water bath, stirring to obtain mixed solution, placing mixed solution in a container, charging with nitrogen gas and sealing container at room temperature for 8-12 hours. USE - Preparation of hyaluronic acid/graphene/polyacrylamide composite hydrogel used as artificial skin, ligament, tendon and other materials, and in tissue engineering applications. ADVANTAGE - The prepared hydrogel has excellent biocompatibility, mechanical properties and toughness.