• 专利标题:   Graphene nanomaterial used to prevent increase in volume of adipose tissue and/or formation of fatty lumps, and reduce cellulitis, wrinkles and/or varicose veins, comprises graphene nanofibers, graphene oxide and/or reduced graphene oxide.
  • 专利号:   EP3597595-A1, WO2020016319-A1
  • 发明人:   MARTINEZ ROVIRA M, MARTINEZ ROVIRA J A, LAVIN LOPEZ M D P, ROMERO IZQUIERDO A, RODRIGUEZ PUYOL M, RODRIGUEZ PUYOL D, DE FRUTOS GARCIA S, GRIERA MERINO M, HATEM VAQUERO M A, OROZCO AGUDO A I
  • 专利权人:   GRAPHENANO MEDICAL CARE SL, GRAPHENANO MEDICAL CARE SL
  • 国际专利分类:   A61K008/04, C01B032/18, C01B032/182, C01B032/198
  • 专利详细信息:   EP3597595-A1 22 Jan 2020 C01B-032/18 202011 Pages: 26 English
  • 申请详细信息:   EP3597595-A1 EP382533 17 Jul 2018
  • 优先权号:   EP382533

▎ 摘  要

NOVELTY - Graphene nanomaterial comprises graphene nanofibers, graphene oxide and/or reduced graphene oxide, where the graphene nanomaterial has a particle size distribution dn(90) of less than or equal to 0.6 mu m in number of particle and a dv(90) of less than or equal to 80 mu m in volume particle, as measured by laser diffraction particle analyzer. USE - The nanomaterial is useful: as a cosmetic to treat the skin and reduce adipose tissue of the skin, preferably fat in the hypodermis; for preventing or reducing the increase in the volume of adipose tissue and/or the formation of fatty lumps; and for reducing cellulitis, wrinkles and/or varicose veins (all claimed). Test details are described but no results given. ADVANTAGE - The nanomaterial has: Brunauer-Emmett-Teller specific surface area of 100-500 (preferably 300-350) m2/g; impurities of less than 0.01 wt.%; low or no toxicity and good biocompatibility. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparing the product from raw graphene nanofibers, graphene oxide or reduced graphene oxide, comprising (a) purifying the raw graphene material, preferably using a strong acid, to remove any metal or impurity present in the graphene raw material, (b) reducing the particle size of the purified graphene nanomaterial, preferably through an exfoliation process, to a particle size distribution, and (c) optionally subjecting the obtained product to a depyrogenization process.