• 专利标题:   Three-dimensional graphene-collagen composite support comprises three-dimensional graphene support, and collagen fibers are bonded to the surface of the three-dimensional graphene support.
  • 专利号:   CN107432952-A
  • 发明人:   CHENG G, JIANG Z, MA Q, MA X, XIAO M, YANG L, ZHANG D
  • 专利权人:   UNIV SHANGHAI, CHINESE ACAD SCI SUZHOU NANOTECH NANO
  • 国际专利分类:   A61L027/08, A61L027/24, A61L027/50, A61L027/54, A61L027/56, D01D005/00, D04H001/30, D04H001/728
  • 专利详细信息:   CN107432952-A 05 Dec 2017 A61L-027/08 201812 Pages: 9 Chinese
  • 申请详细信息:   CN107432952-A CN10353589 25 May 2016
  • 优先权号:   CN10353589

▎ 摘  要

NOVELTY - Three-dimensional graphene-collagen composite support comprises three-dimensional graphene support, and collagen fibers are bonded to the surface of the three-dimensional graphene support. The three-dimensional graphene-collagen composite support has three-dimensional porous structure. The pores in the three-dimensional porous structure having pore size is larger than 1 mu m and smaller than 100 mu m. USE - Used as three-dimensional graphene-collagen composite support. ADVANTAGE - The support: has simple preparation method, low cost, promotes the proliferation and differentiation of neural stem cells. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for (1) preparing three-dimensional graphene-collagen composite support, providing three-dimensional graphene support, and setting the support in the threedimensional graphene strength is 5-10 kV of high voltage electrostatic field, and combining the collagen fiber with three-dimensional graphene support surface under the action of electrostatic field, forming three-dimensional graphene-collagen composite support, the three-dimensional graphene-collagen composite support has threedimensional porous structure, the pore diameter of the hole contained in the three-dimensional porous structure is greater than 1 mu m and less than 100 mu m, the porosity is greater than 98% and the diameter of the collagen fiber is more than 10 nm but less than 10 mu m; and (2) use of three-dimensional graphene-collagen composite support for cells comprising neural stem cells, neural progenitor cells, mesenchymal stem cells, and fibroblasts.