▎ 摘　　要

NOVELTY - Medicine slow-release controllable polyether-ether ketone (PEEK) implant comprises medicine carrying area and solid area. The drug-loading area comprises second polyether ether ketone substrate, drug loading medium and drug or active factor loaded on the second polyether-ether ketone substrate through drug loading material. The second polyethylene substrate has a concave hole connected with each other less than or equal to 10 microns. The strength of the first polyethyl ether ketone substrate satisfies that the implant keeps the original structure during use. The first polyether ether ketone substrates and the second polyether-ether ketone substrates are obtained by laser selective sintering printing. USE - Medicine slow release controllable polyether-ether-ketone implant is useful for treating bone defect. ADVANTAGE - The implant controls the slow release rate and time of the drug or active factor by using the non-used porosity, which solves the problem that the existing surface coating drug-loading technology coating is easy to fall off, slow release time is too fast and pore-forming technology porosity is not controllable, and harmful group are introduced. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing drug sustained-release controllable polyether-ether-ketone implant, which involves: (a) carrying out heat treatment on polyether-ether-ketone powder to obtain a model of a body to be implanted, and dividing solid area and drug-loading area; (b) dividing the model in a Z axis manner, and scanning solid area and drug loading area of each layer respectively by using two lasers until the selective laser sintering printing is completed; and (c) carrying out sand blasting or air jet treatment and ultrasonic cleaning on the printed portion, placing printed portion into a buffer solution in which a medicine or an active factor and medicine carrying medium are dissolved, stirring under the negative pressure condition, loading medicine or the active factor on the implant through the medicine carrying medium, and obtaining implant after the printed part is taken out, cleaned and dried. DESCRIPTION OF DRAWING(S) - The drawing shows a flow chart of a method for preparing polyetheretherketone implant with controllable drug release. (Drawing includes non-English language text).