▎ 摘　　要

NOVELTY - Micro-RNA-graphene-gold complex comprises gold nano-particle, microRNA and graphene. USE - Micro-RNA-graphene-gold complex used in thermotherapy and nano drug delivery system for treating drug-resistant ovarian cancer. ADVANTAGE - The micro-RNA-graphene-gold complex reduces toxicity and side effect, avoids multi-drug resistance, increases treatment effect and induces ovarian cancer cell apoptosis. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing micro-RNA-graphene-gold complex, which involves: (A) obtaining microRNA gold nan-particle carrier using drip sodium, hexadecyl trimethyl ammonium bromide, chloroauric acid and water; (B) obtaining graphene oxide carrier-P-glycoprotein antibody complex using graphene, sodium chloride, water, sulfuric acid, potassium permanganate solution, hydrogen peroxide, sodium hydroxide, chloro acetic acid, carboxylic acid and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; and (C) mixing microRNA gold nan-particle carrier, graphene oxide carrier-P-glycoprotein antibody complex and chitosan solution ultrasonically for 2 hours in vacuum to obtain product.