▎ 摘　　要

NOVELTY - A device comprises biomolecule such as protein comprising histidine tag in electronic communication with graphene body, the biomolecule having an optical absorption peak at around a particular wavelength of excitation illumination, where the protein is bound to the graphene by a peptide sequence. The protein comprises chitin binding protein, maltose binding protein, glutathione-S-transferase and/or epitope tag. The graphene comprises Diimide-activated amidation. The protein comprises flavoprotein, tryptophan or heme containing protein where iron is substituted by zinc. USE - As bioelectronic device to functionalize graphene field effect transistors with fluorescent proteins to yield hybrids. ADVANTAGE - The device provides a pathway for production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. The method using the device can functionalize graphene field effect transistors (FETs) with fluorescent proteins to yield hybrids that respond to light at wavelengths defined by the optical absorption spectrum of the protein. The devices may also include graphene in electronic communication with a biomolecule that preferentially binds to a particular analyte. The methods are robust and reproducible processes for binding His-Tagged proteins to graphene FETs. This in turn provides a pathway for construction of bio/nano hybrids integrating desirable functionalities of both components. The FP-GFET hybrids present a new class of tunable photodetectors with photocurrent responses in a wavelength range determined by the absorption spectrum of the bound fluorescent protein. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for method to functionalize graphene field effect transistors with fluorescent proteins to yield hybrids involving contacting a biomolecule such as protein, receptor, ligand, enzyme and antibody comprising histidine residue to a graphene body such that the biomolecule and graphene body are placed into electronic communication with one another, where the histidine residue interacts with molecules associated with the graphene, and where the electronic communication between the protein and the graphene body includes an interaction between a nickel-nitriloacetic acid group and a histidine residue.