• 专利标题:   Thermal radiating nanomedicine having strong effect for killing tumor cells and treating cancer, comprises amphiphilic graphene, nano gold particles supported on amphiphilic graphene surface connected with tumor target molecule.
  • 专利号:   CN107281489-A, CN107281489-B
  • 发明人:   LUO J, XU Y, JIANG H, NI X, ZHU W, SUN Z, JIAO Y, ZHANG Q
  • 专利权人:   CHANGZHOU SECOND PEOPLES HOSPITAL
  • 国际专利分类:   A61K041/00, A61K047/58, A61K047/60, A61K047/64, A61P035/00
  • 专利详细信息:   CN107281489-A 24 Oct 2017 A61K-041/00 201778 Pages: 10 Chinese
  • 申请详细信息:   CN107281489-A CN10318133 08 May 2017
  • 优先权号:   CN10318133

▎ 摘  要

NOVELTY - Thermal radiating nanomedicine, comprises amphiphilic graphene, nano gold particles supported on amphiphilic graphene surface connected with tumor target molecule. USE - Thermal radiating nanomedicine for treating cancer (claimed). ADVANTAGE - The thermal radiating nanomedicine having strong effect for killing tumor cells, enables to treat cancer through heat treatment composite proton or neutron therapy. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing thermal radiating nanomedicine, which involves: (A) modifying diisocyanate on surface of graphene oxide; (B) adding carboxyl group-containing polymer and tumor targeting molecule to obtain amphiphilic graphite; (C) growing gold nanoparticles insitu on surface of obtained amphiphilic graphite; and (D) adding amino-containing tumor targeted molecule with amphiphilic graphene carboxyl group to obtain the desired thermal radiating nano-medicine.