▎ 摘　　要

NOVELTY - An implantable enzyme-free sensor electrode material has a core-shell structure in which a core comprises a transition metal and/or a transition metal compound, and a shell comprises a conductive composition comprising a mixture of conductive polymer and conductive inorganic substance. The surface of the core is distributed with noble metal. USE - Electrode material used in preparation of implantable enzyme-free sensor (all claimed) used as in-vivo continuous monitoring biosensor. ADVANTAGE - The electrode material has high catalytic activity, excellent conductivity, high detection sensitivity and biological compatibility, and provides sensor capable of monitoring for a long time. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) preparation of implantable enzyme-free sensor electrode material, which involves dispersing the transition metal powder and/or transition metal compound powder in a solvent, adding a surfactant, stirring until dissolved or evenly dispersed, adding the noble metal, the conductive inorganic substance and the conductive polymer in order, stirring until evenly mixed, and centrifuging; (2) implantable enzyme-free sensor; and (3) preparation of implantable enzyme-free sensor, which involves ultrasonically dispersing the electrode material in an ethanol solution to obtain an electrode material dispersion, coating the electrode material dispersion on the substrate surface of the working electrode, drying at room temperature to obtain an electrode material modification layer, and assembling the working electrode with the electrode material modification layer, the counter electrode and the reference electrode to obtain a composite electrode.