▎ 摘　　要

NOVELTY - Soluble micro-needle comprises at least one needle body located on the needle seat. The needle body comprises a first middle section, a second middle section and a needle tip section. The first middle section is located on the needle seat. The second middle section is located between the first middle section and the needle tip section. The density of the second middle section is more than the density of the needle tip section and the first middle section. The needle tip section contains medicine active ingredient. USE - Soluble micro-needle. ADVANTAGE - The soluble micro-needle can obviously improve the local administration concentration, and realizes accurate dosing of fixed-point quantification. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparing the soluble micro-needle, comprises taking the medicine active ingredient solution in the micro-needle mold, vacuumizing, curing for the first time to obtain the needle mold loaded with needle tip section, taking the second polymer material slurry is cast on the needle mold loaded with needle tip section, vacuumizing, second curing to obtain the needle tip section and the second middle section of the micro-needle mold, taking the first polymer material slurry is cast on the needle tip section and the second middle section of the micro-needle mold, vacuumizing, third curing to obtain the needle tip section, the second middle section and the first middle section of the micro-needle mold, taking the third polymer material slurry is cast on the needle tip section, the second middle section and the first middle section of the micro-needle mold, vacuumizing, and fourth curing to obtain the soluble micro-needle.