• 专利标题:   Gas-phase explosives sensitive adsorbent material obtained by activating carboxyl groups on surface of graphene oxide to, stabilizing using 2-(2-pyridyldithio)ethylamine hydrochloride to generate coupling intermediate, and carrying out disulfide exchange reaction with 6-aminohexanethiol.
  • 专利号:   CN115554985-A
  • 发明人:   WANG T, YANG J, XI X, XIAO D, WU X, DONG P
  • 专利权人:   UNIV NAT DEFENSE TECHNOLOGY
  • 国际专利分类:   B01J020/22, B01J020/30, G01N029/036, G01N029/22
  • 专利详细信息:   CN115554985-A 03 Jan 2023 B01J-020/22 202314 Chinese
  • 申请详细信息:   CN115554985-A CN11123100 15 Sep 2022
  • 优先权号:   CN11123100

▎ 摘  要

NOVELTY - Gas-phase explosives sensitive adsorbent material, obtained by activating carboxyl groups on the surface of graphene oxide to generate active lipids by N-(3-dimethylaminopropyl)-N'-ethyl carboxydiimine hydrochloride, then stabilizing resulting active lipid by N-hydroxysuccinimide, then using 2-(2-pyridyldithio)ethylamine hydrochloride to form an amide bond with the activated carboxyl group and generate a GO-S-S-Py coupling intermediate, then GO/PDEA-6MNA, a sensitive adsorption material for gas-phase explosives, is obtained by disulfide exchange reaction with 6-aminohexanethiol. USE - The gas-phase explosives sensitive adsorbent material is useful in gas phase explosive sensor chip used for detecting gas phase explosives. ADVANTAGE - The sensitive adsorption material: can be deposited as a nanometer coating on the sensing area of the surface acoustic wave device to form a sensor chip for gas phase explosives; has good specificity, high sensitivity, low cost, fast response time and recovery time; in sensor chip can realize ultra-high sensitivity detection of gas-phase explosives. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: Preparing sensitive adsorbent material for gas-phase explosives, comprising (i) adding graphene oxide nanosheets into water, and ultrasonically dispersing to obtain graphene oxide dispersion, (ii) adding N-(3-dimethylaminopropyl)-N'-ethylcarboxydiimine hydrochloride solution to the graphene oxide dispersion obtained in step (i) to activate the carboxyl groups on the surface of graphene oxide to generate active lipids, (iii) adding N-hydroxysuccinimide solution to the activated sample to protect the active lipid generated, (iv) adding 2-(2-pyridyldithio)ethylamine hydrochloride solution in the solution obtained in step (iii), coupling is performed to generate GO-S-S-Py coupling intermediates by forming amide bonds with activated carboxyl groups, and (v) adding 6-aminohexanethiol solution to the solution for coupling, and generating gas-phase explosive sensitive adsorption material GO/PDEA-6MNA through disulfide exchange reaction; Gas phase explosives sensor chip, comprising a surface acoustic wave device and gas-phase explosive-sensitive adsorption material arranged in the sensing area of the surface acoustic wave device; and Use of gas phase explosive sensor chip in detecting gas phase explosives.