• 专利标题:   Protein tyrosine phosphatase selective inhibitor useful in preparing medicine for treating diabetes, tumor and obesity, prepared by e.g. mixing vanadium compound with protein tyrosine phosphatase selective ligand and loading obtained compound on functionalized carrier.
  • 专利号:   CN113801156-A, CN113801156-B
  • 发明人:   DONG Y, FENG B, YANG X
  • 专利权人:   UNIV PEKING
  • 国际专利分类:   A61K031/28, A61P003/04, A61P003/10, A61P035/00, C07F009/00
  • 专利详细信息:   CN113801156-A 17 Dec 2021 C07F-009/00 202237 Chinese
  • 申请详细信息:   CN113801156-A CN11194384 13 Oct 2021
  • 优先权号:   CN11194384

▎ 摘  要

NOVELTY - Protein tyrosine phosphatase selective inhibitor is claimed. The protein tyrosine phosphatase selective inhibitor is functionalized carrier-protein tyrosine phosphatase selective ligand-vanadium coordination complex. USE - The protein tyrosine phosphatase selective inhibitor is useful in preparing medicine for treating diabetes, tumor and obesity (claimed). ADVANTAGE - The selective inhibitor: can improve the enzyme inhibitory activity while reducing the efficient use concentration without causing adverse reactions to the body. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) Medicinal composition comprising protein tyrosine phosphatase selective inhibitor and auxiliary materials; and (2) Preparing protein tyrosine phosphatase selective inhibitor, comprising mixing vanadium compound with protein tyrosine phosphatase selective ligand, and loading the obtained compound on the functionalized carrier to form functionalized carrier-protein tyrosine phosphatase selective ligand-vanadium coordination complex.