▎ 摘　　要

NOVELTY - Preparing mineralized fiber reinforced three-dimensional porous support comprises mixing silk fibroin aqueous solution with the graphene oxide dispersion liquid, concentrating the mixed solution, preparing the mixed solution into silk fibroin/graphene oxide composite fiber felt, post-processing with ethanol aqueous solution, taking out, drying, shearing to obtain short fibers, immersing the silk fibroin/graphene oxide composite fiber felt in treatment solution, taking out, drying, immersing dried silk fibroin/graphene oxide composite fiber felt, mineralizing, taking out, drying, dissolving sodium alginate in water to obtain a sodium alginate aqueous solution, blending with agarose aqueous solution to obtain a sodium alginate/agarose mixed solution, mixing the short fiber after mineralizing and drying with the sodium alginate/agarose mixed solution and placing the mixed solution into a low-temperature refrigerator, freezing into a solid, placing into a freeze dryer to obtain product. USE - The mineralized fiber reinforced three-dimensional porous support is useful in fields of bone tissue engineering and biomedical materials (claimed). ADVANTAGE - The three-dimensional porous support has good biological compatibility and has excellent mechanical property. DETAILED DESCRIPTION - Preparing mineralized fiber reinforced three-dimensional porous support comprises (a) mixing the silk fibroin aqueous solution with the graphene oxide dispersion liquid, mixing uniformly, concentrating the mixed solution to the silk fibroin to a concentration, (b) preparing the mixed solution of step (a) into silk fibroin/graphene oxide composite fiber felt by electro spinning method, (c) post-processing the silk fibroin/graphene oxide composite fiber felt with 80 vol.% ethanol aqueous solution, taking out, drying, (d) shearing the silk fibroin/graphene oxide composite fiber felt in step (c) at high-speed to obtain short fibers, (e) immersing the silk fibroin/graphene oxide composite fiber felt after high-speed shearing in the treatment solution for a period of time, taking out, drying, (f) immersing the dried silk fibroin/graphene oxide composite fiber felt in step (e) into 10 times the simulated body fluid, mineralizing, taking out, drying, (g) dissolving sodium alginate in water to obtain a sodium alginate aqueous solution, blending with 4% agarose aqueous solution to obtain a sodium alginate/agarose mixed solution, (h) mixing the short fiber after mineralizing and drying in the step (f) with the sodium alginate/agarose mixed solution in step (g) and (i) placing the mixed solution of step (h) into a low-temperature refrigerator, freezing into a solid, placing into a freeze dryer to obtain a mineralized silk fibroin/graphene oxide fiber-reinforced sodium alginate/agarose three-dimensional porous support. An INDEPENDENT CLAIM is also included for mineralized silk fibroin/graphene oxide fiber-reinforced sodium alginate/agarose three-dimensional porous support.