▎ 摘　　要

NOVELTY - Preparation of doped titanium dioxide ceramic film involves (S1) taking vascular stent material comprising medical magnesium alloy as substrate, (S2) pre-processing substrate by degreasing using sodium carbonate, grinding, ultrasonically cleaning with ethanol and drying, (S3) feeding dried substrate in sputtering coating device, using magnesium oxide target as sputtering source, preparing magnesium oxide transition layer under argon atmosphere, (S4) mixing butyl titanate and ethanol to obtain solution (A), mixing ethanol and distilled water, adding graphene to obtain graphene dispersion solution, adjusting pH with glacial acetic acid to obtain solution (B), dripping solution (A) in solution (B), aging to obtain sol, (S5) preparing graphene-doped titanium dioxide ceramic film by lifting method, coating sol at a lifting rate of 5-8 cm/minute, drying, sintering at 300-350 degrees C, coating multiple times, and annealing at 450-500 degrees C, to obtaining film with 3-5 mu m thickness. USE - Preparation of doped titanium dioxide ceramic film by sol-gel method. ADVANTAGE - The method shows that when doping amount is 5% and 10.8%, the hemolysis rate of titanium dioxide ceramic film on the surface of vascular stent can be lower than 10% and when doping amount is 7.3%, the hemolysis rate is as low as 2.1%. DETAILED DESCRIPTION - Preparation of doped titanium dioxide ceramic film by sol-gel method, involves (S1) taking vascular stent material comprising medical magnesium alloy as substrate, (S2) pre-processing substrate by degreasing using sodium carbonate, grinding, ultrasonically cleaning with ethanol and drying, (S3) feeding dried substrate in sputtering coating device, using magnesium oxide target as sputtering source, preparing magnesium oxide transition layer under argon atmosphere, where power supply power is 60-80 W, at 60-90 sccm argon gas flow rate and at 150-180 degrees C substrate temperature, and sputtering for 18-30 minutes, (S4) mixing 5-8 mol butyl titanate and 40-50 mol ethanol to obtain solution (A), mixing 40-50 mol ethanol and 4-10 mol distilled water, adding graphene to obtain graphene dispersion solution, adjusting pH with 3.5-5 mol glacial acetic acid to obtain solution (B), continuously stirring and dripping solution (A) in solution (B), aging for 12-24 hours to obtain sol, (S5) preparing graphene-doped titanium dioxide ceramic film by lifting method, coating sol at a lifting rate of 5-8 cm/minute, and drying at 80-90 degrees C for 20-25 minutes, at 45-50 degrees C for 20-30 minutes, and at 25-30 degrees C for 30-50 minutes, naturally cooling to room temperature, sintering at 300-350 degrees C for 30-40 minutes, coating multiple times based on film thickness, and annealing at 450-500 degrees C for 1-2 hours, to obtain graphene-doped titanium dioxide ceramic film with 3-5 mu m thickness.