• 专利标题:   Kit useful for analyzing DNA cut enzyme and methyl transferase activity, and inhibitor of methyl transferase enzyme, comprises graphene oxide, double strand DNA substrate, luminescent probe material, and enzyme cut portion.
  • 专利号:   KR2013017271-A, KR1818177-B1
  • 发明人:   MIN D H, LEE J E
  • 专利权人:   KOREA ADV INST SCI TECHNOLOGY, KOREA ADVANCED INST SCI TECHNOLOGY
  • 国际专利分类:   C12Q001/34, C12Q001/48
  • 专利详细信息:   KR2013017271-A 20 Feb 2013 C12Q-001/34 201327 Pages: 18
  • 申请详细信息:   KR2013017271-A KR079610 10 Aug 2011
  • 优先权号:   KR079610

▎ 摘  要

NOVELTY - Kit comprises graphene oxide, double strand DNA substrate in which a single strand DNA tail capable of adhering with graphene oxide is included at first terminal, luminescent probe material is marked which darkens when getting close to the graphene oxide at a second terminal, and enzyme cut portion is included between the first terminal and the second terminal. USE - The kit is useful for analyzing DNA cut enzyme and methyl transferase activity, and inhibitor of methyl transferase enzyme (all claimed). ADVANTAGE - The kit analyzes DNA cut enzyme and methyl transferase activity rapidly and correctly, and can be widely utilized for a time-efficient parallel analysis. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for method of screening DNA cut enzyme or methyl transferase, and inhibitor of methyl transferase enzyme using the kit.