• 专利标题:   Preparation method of p-menthyl-3,8-diol, involves taking citronellal as raw material, oxidized graphene as catalyst, and water as solvent, and performing cyclization hydration reaction.
  • 专利号:   CN108341740-A
  • 发明人:   JIANG H, CAO X, JIANG B
  • 专利权人:   SHANGHAI ORGANIC CHEM INST
  • 国际专利分类:   C07C029/00, C07C029/76, C07C035/08
  • 专利详细信息:   CN108341740-A 31 Jul 2018 C07C-029/00 201862 Pages: 7 Chinese
  • 申请详细信息:   CN108341740-A CN10368992 23 Apr 2018
  • 优先权号:   CN10368992

▎ 摘  要

NOVELTY - The preparation method of p-menthyl-3,8-diol involves taking citronellal as raw material, oxidized graphene as catalyst, and water as solvent, and performing cyclization hydration reaction. USE - Preparation method of p-menthyl-3,8-diol. ADVANTAGE - The method enables preparation of p-menthyl-3,8-diol with low requirements on equipment, by simple and environmentally-friendly processes. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for purification method of cis and trans configurations of p-menthyl-3,8-diol, which involves dissolving p-menthyl-3,8-diol obtained by cyclization hydration reaction in an organic solvent at 50-80 degrees C to obtain clear solution, where the organic solvent is ethyl acetate and/or n-hexane, lowering the temperature to room temperature, leaving still for crystallization, filtering, and drying to obtain cis-p-menthyl-3,8-diol, concentrating the mother liquor after crystallization filtration, and distilling under reduced pressure to obtain trans-p-menthyl-3,8-diol.