• 专利标题:   Nanotheranostic used for phototherapy, comprises aza-boron-dipyrromethene for photodynamic therapy and reduced nanographene oxide with photothermal therapy effect.
  • 专利号:   TR202022193-A2
  • 发明人:   ALGI F, SOYLUKAN C
  • 专利权人:   UNIV AKSARAY REKTOERLUEGUE
  • 国际专利分类:   A61N001/00, A61N001/04, A61N001/08, A61P035/00
  • 专利详细信息:   TR202022193-A2 21 Jun 2021 A61N-001/00 202347 Pages: 43
  • 申请详细信息:   TR202022193-A2 TR022193 29 Dec 2020
  • 优先权号:   TR022193

▎ 摘  要

NOVELTY - A nanotheranostic comprises aza-boron-dipyrromethene (AzaBODIPY) (A) for photodynamic therapy and reduced nanographene oxide (NrGO) (B) with photothermal therapy effect. USE - Nanotheranostic for phototherapy used in bioimaging, biotechnology, medical and pharmaceutical sectors working on cancer disease imaging, diagnosis and treatment of hospital and medical center. ADVANTAGE - The nanotheranostic does not has toxic effect on healthy tissue, performs FDT, FTT and live cell imaging, easily evades the immune system, and passively targets cancerous tissues. DESCRIPTION OF DRAWING(S) - The drawing shows a flow chart of the method for producing aza-boron-dipyrromethene. 10Potassium carbonate taking step 20Hydroxyacetophenone adding step 30Dissolving step 40Propargyl bromide adding step 50Mixing step 60Ice water adding step 70Draining step 80Synthesizing step