• 专利标题:   Thin-film-based assembly for analyzing e.g. proteins in graphene liquid cell, has support base and thin film placed on support base, where spherical nanoparticle is placed between thin film and support base.
  • 专利号:   WO2023282753-A1, NL2028670-B1
  • 发明人:   VAN DEURSEN P M G
  • 专利权人:   VITROTEM BV
  • 国际专利分类:   G01N001/28, G01N033/487, H01J037/20
  • 专利详细信息:   WO2023282753-A1 12 Jan 2023 G01N-001/28 202309 Pages: 20 English
  • 申请详细信息:   WO2023282753-A1 WONL050400 08 Jul 2022
  • 优先权号:   NL2028670

▎ 摘  要

NOVELTY - The assembly (100) has a thin film (102) placed on a support base (101). The thin film includes a thickness of less than 10 nanometer. A spherical nanoparticle (106) is provided between the thin film and support base, and functionally constitutes a spacer between the thin film and base. The spherical nanoparticles account for 50-90% in a portion of a space (104) between the thin film and the base. A cell includes a circumference formed by the thin film locally being in contact with the base. USE - Thin-film-based assembly for analyzing a sample such as proteins, vesicles and viruses, in a cell (all claimed) i.e. graphene liquid cell. ADVANTAGE - The spherical nanoparticles provide a form of control over the space that is formed between the support base and the thin film. The thin film provides a relatively high degree of transparency, thus allowing a relatively precise analysis of what is inside the space and what happens inside the space. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a method for forming a thin-film-based assembly. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic cross-sectional view of a graphene liquid cell comprising spherical nanoparticles that functionally constitute spacers. 100Thin-film-based assembly 101Support base 102Thin film 104Space 106Spherical nanoparticle