▎ 摘　　要

NOVELTY - Detection sensor comprises silicon dioxide substrate, graphene channel and reaction cavity, where the silicon dioxide substrate surface is provided with metal electrode, the metal surface of the electrode has graphene channel, the graphene channel is fixed on surface of sensor using modified 1-pyrenebutanoic acid succinimidyl ester. USE - The sensor is useful for detecting tumor marker (claimed) and target molecule. ADVANTAGE - The sensor is prepared by simple method, and convenient to use, and enables to detect tumor marker with high sensitivity and specificity. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for method for preparing the detection sensor.