• 专利标题:   Functionalized graphene-containing microcapsules used in cladding of hydrophobic drugs, comprise capsule wall, which is crosslinked membrane formed of solution of sulfhydrylized graphene, and oil phase loaded with hydrophobic drug.
  • 专利号:   CN105310998-A
  • 发明人:   CUI X, DONG L, WANG H
  • 专利权人:   UNIV JILIN
  • 国际专利分类:   A61K031/17, A61K031/337, A61K031/357, A61K031/4745, A61K047/04, A61K009/50
  • 专利详细信息:   CN105310998-A 10 Feb 2016 A61K-009/50 201650 Pages: 9 English
  • 申请详细信息:   CN105310998-A CN10736120 03 Nov 2015
  • 优先权号:   CN10736120

▎ 摘  要

NOVELTY - Functionalized graphene-containing microcapsules comprise capsule wall, which is a crosslinked membrane formed using an aqueous solution of sulfhydrylized graphene obtained by modifying a compound containing sulfhydryl and amino or bio-molecules, and core material, which is an oil phase loaded with hydrophobic drugs. The size of microcapsules is 0.2-30 mu m. USE - Functionalized graphene-containing microcapsules used in cladding of hydrophobic drugs. ADVANTAGE - The functionalized graphene-containing microcapsules are capable of achieving controlled release of drugs, and have high drug loading capacity, and can be prepared by simple, easy, efficient and rapid method. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of functionalized graphene-containing microcapsules, which involves ultrasonically radiating aqueous solution containing sulfhydrylized graphene and oil phase loaded with the hydrophobic drugs.