• 专利标题:   Functionalizing graphene sensor surface, involves e.g. binding multiple molecular complexes to graphene layer surface, and coupling detector molecules to first subset of multiple molecular complexes.
  • 专利号:   WO2023076470-A1, US2023135374-A1
  • 发明人:   BORRELLO E, RUBY T, FELTRUP T
  • 专利权人:   GRAPHENEDX INC, BORRELLO E, RUBY T, FELTRUP T, GRAPHENEDX INC
  • 国际专利分类:   G01N033/543, G01N033/487
  • 专利详细信息:   WO2023076470-A1 04 May 2023 G01N-033/543 202340 Pages: 34 English
  • 申请详细信息:   WO2023076470-A1 WOUS048014 27 Oct 2022
  • 优先权号:   US273853P, US969614

▎ 摘  要

NOVELTY - Functionalizing graphene sensor surface, comprises: (a) providing a graphene layer including a surface; (b) binding multiple molecular complexes to the surface of the graphene layer, where each molecular complex includes: a linker molecule configured to couple to the sensor surface at a first linker position, and a binding molecule coupled to the linker molecule at a second linker position different from the first linker position; (c) coupling at least one detector molecules to a first subset of the multiple molecular complexes; and (d) coupling at least one passivation agents to a second subset of the molecular complexes, at least some of the molecular complexes of first subset being different from molecular complexes of the second subset. USE - The method is useful for functionalizing graphene sensor surface. ADVANTAGE - The method is economical and reliable. DESCRIPTION OF DRAWING(S) - The drawing shows a flowchart illustrating the method for functionalizing graphene sensor surface. 610Graphene layer providing step 620Binding step 630Molecular complex coupling step 640Binding molecule coupling step 650Detector molecules coupling step