▎ 摘　　要

NOVELTY - Preparation method of hemoperfusion device graphene filler for decomposing arginine involves dispersing graphene particles in cold sulfuric acid, adding sodium nitrate and potassium permanganate, performing reaction, performing suction filtration after adding distilled water and hydrogen peroxide, washing and drying respectively to obtain surface-activated graphene particles, adding surface-activated graphene particles to continue the reaction, adding deionized water, hydrochloric acid, and sodium nitrite, after solution reaction, filtering, washing and drying the particle, adding γ-aminopropyltriethoxysilane to absolute ethanol, stirring the solution, adding surface-functionalized graphene oxide particles, filtering, washing and drying to obtain surface silicone-functionalized graphene oxide particles, adding the graphene oxide particles functionalized with silicone on the surface to the phosphate buffer, adding ADI for reaction, filtering, washing and drying the product. USE - The method is useful for preparation of hemoperfusion device graphene filler for decomposing arginine in blood. DETAILED DESCRIPTION - Preparation method of hemoperfusion device graphene filler for decomposing arginine involves dispersing graphene particles in cold sulfuric acid, adding sodium nitrate and potassium permanganate, performing reaction after slowly adding deionized water and reacting, performing suction filtration after adding distilled water and hydrogen peroxide successively to stop the reaction, washing and drying respectively to obtain surface-activated graphene particles, adding surface-activated graphene particles to continue the reaction after adding p-(β ethylsulfone sulfone group) aniline to deionized water for reaction, adding deionized water, hydrochloric acid, and sodium nitrite, after solution reaction, filtering, washing and drying the particle, obtaining graphene oxide particle of surface functionalization, adding γ-aminopropyltriethoxysilane to absolute ethanol, stirring the solution, adding surface-functionalized graphene oxide particles for reaction, after the reaction is completed, filtering the solution, washing and drying to obtain surface silicone-functionalized graphene oxide particles, adding the graphene oxide particles functionalized with silicone on the surface to the phosphate buffer, adding ADI for reaction, filtering, washing and drying the product.