• 专利标题:   Preparing nerve electrode modified by nanometer material, comprises e.g. performing roughening treatment on surface of recording site of nerve electrode, and using deionized water to wash sequentially into acetone.
  • 专利号:   CN115813399-A
  • 发明人:   WANG H, WANG Y, LIU S, ZHANG X
  • 专利权人:   UNIV TIANJIN
  • 国际专利分类:   A61B005/263, A61B005/265, A61B005/268, A61B005/293, C25D005/10, C25D009/04
  • 专利详细信息:   CN115813399-A 21 Mar 2023 A61B-005/293 202332 Chinese
  • 申请详细信息:   CN115813399-A CN11579165 08 Dec 2022
  • 优先权号:   CN11579165

▎ 摘  要

NOVELTY - Preparing a nano-material-modified neural electrode, comprises (1) roughening the surface of the recording site of the neural electrode, rinsing with deionized water, sequentially introducing it into acetone and anhydrous ethanol for ultrasonic cleaning, and drying; (2) using the electrode as the working electrode, platinum electrode as the counter electrode, and silver/silver chloride as the reference electrode, connecting them to an electrochemical workstation, adding a nano-material aqueous solution with a concentration of 0.5-10 mg/ml as an electrodeposition working solution into an electrolytic cell for deposition, with a deposition layer of 1-10 layers to modify the surface of the recording site of the neural electrode; (3) using polyimide or poly-para-xylylene to insulate the other parts of the neural electrode except for the recording site. USE - Preparation method of nerve electrode modified by nanometer material used as diagnostic tool for nervous system disease e.g. cerebral apoplexy, Parkinson disease and epilepsy. ADVANTAGE - The method is capable of improving nerve electrode biological compatibility, collecting sensitivity, and long-term stability, under the premise of keeping the original space selectivity of the nerve electrode, the nano-material modified nerve electrode impedance is reduced. The electrode surface has a controllable micro-nano structure so as to have a large effective reaction surface, improving the electrochemical performance and detection sensitivity of the nerve electrode. The small size of the nanomaterial, large specific surface area, good biocompatibility, and so characteristics, of electrode-modified material, can obviously accelerate the electronic transmission rate. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a nerve electrode modified by nano material prepared by the method. DESCRIPTION OF DRAWING(S) - The drawing shows a structure characterization of nano-material modified electrode. (Drawing includes non-English language text).