▎ 摘　　要

NOVELTY - Synthesis of functionalized nanoparticle-graphene quantum dots nanocomposites comprises irradiating mixture containing carbon source, nanocomposite core precursor powder and ligand source with electromagnetic radiation. USE - Synthesis of functionalized nanoparticle-graphene quantum dots nanocomposites used for inhibiting bacterial growth, particularly Staphylococcus aureus and Pseudomonas aeruginosa. A determination of bacterial minimum inhibitory concentration of functionalized nanoparticle-graphene quantum dots nanocomposites, particularly silver graphene quantum dots (Ag-GQDs), was conducted by preparing bacterial suspension of Staphylococcus aureus and Pseudomonas aeruginosa having 107 CFU/mL concentration, adding 150 mu L fresh Mueller Hinton (MH) broth, 20 mu L bacterial suspension and 30 mu L different concentrations of Ag-GQDs in 96-well plate, incubating microplates at 37 degrees C for 24 hours under static conditions, and reading optical density of plate at 600 nm before and after incubation. Total inhibition of Pseudomonas aeruginosa was observed when Ag-GQDs were used at 150 mu g/mL, and of Staphylococcus aureus at 320 mu g/mL. The Ag-GQDs at 320 mu g/mL concentration have inhibition zone for Staphylococcus aureus of 12.2 plus minus 0.1 mm, and for Pseudomonas aeruginosa of 13.2 plus minus 0.2 mm. ADVANTAGE - The nanocomposites are soluble in organic and polar solutions having 2-10 nm particle size resulting to high biocompatibility.