• 专利标题:   New protein or peptide comprising amino acid sequences, useful in immunoassay diagnostic kit for detecting presence or absence of immunoglobulins against severe acute respiratory syndrome-coronavirus (SARS-CoV)-2 and diagnosing SARS-CoV-2.
  • 专利号:   BR102020024403-A2, BR102020024403-A8
  • 发明人:   SOCCOL V T, SANTIANI M H, SOCCOL C R, APARECIDO BOSCHERO R, DELA VEDOVA COSTA J M, DO NASCIMENTO FERREIRA G, RAMOS E L P, DE CARVALHO J C, BEIRAO B C B, INGBERMAN M, BOSCHERO R A, COSTA J M D V, FERREIRA G D N, CARVALHO J C D
  • 专利权人:   UNIV FEDERAL PARANA, IMUNOVA ANALISES BIOLOGICAS LTDAME
  • 国际专利分类:   C07K007/08, G01N033/569
  • 专利详细信息:   BR102020024403-A2 10 May 2022 C07K-007/08 202256
  • 申请详细信息:   BR102020024403-A2 BR10024403 30 Nov 2020
  • 优先权号:   BR10024403

▎ 摘  要

NOVELTY - A protein or peptide comprising one or more amino acid sequences of SEQ ID NOs: 1-9 (sequences not given in the patent specification), is new. USE - The protein or peptide is useful in immunoassay diagnostic kit for detecting presence or absence of immunoglobulins M, G, or A against SARS-CoV-2 and determining total and/or separate content of immunoglobulins M, G, or A against SARS-CoV-2 (all claimed), and diagnosing SARS-CoV-2. ADVANTAGE - The protein or peptide enables to detect presence or absence of immunoglobulins against SARS-CoV-2 in an accurate and cost-effective manner high sensitivity and specificity, and enables to diagnose SARS-CoV-2 at an early stage. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) in vitro diagnostic method for detecting presence or absence of immunoglobulins against severe acute respiratory syndrome-coronavirus (SARS-CoV)-2, involves (a) contacting the proteins or peptides with biological sample to form an immune complex, and (b) detecting presence or absence of formed immune complex; and (2) immunoassay diagnostic kit comprising the proteins or peptides (antigens), wash buffer, incubation buffer, secondary antibody, developer solution, stop solution and a manual for using the kit.