• 专利标题:   Synthesizing isocoumarines involve subjecting to Sonogashira cross-coupling reaction followed by intramolecular cyclization, and catalyzing by palladium nanoparticles which is supported on reduced graphene oxide.
  • 专利号:   BR102016029220-A2
  • 发明人:   DA SILVA GOMES R, ALVES MARTINS C, APARECIDA HONORATO G, BEATRIZ A, DE LIMA D P
  • 专利权人:   UNIV FUNDACAO FEDERAL MATO GROSSO DO SUL
  • 国际专利分类:   C07B063/02, C07B037/06, C07C041/06
  • 专利详细信息:   BR102016029220-A2 19 Jun 2018 C07B-063/02 201856 Pages: 8 English
  • 申请详细信息:   BR102016029220-A2 BR10029220 02 Dec 2016
  • 优先权号:   BR10029220

▎ 摘  要

NOVELTY - Synthesizing isocoumarines involes subjecting to Sonogashira cross-coupling reaction followed by intramolecular cyclization, and catalyzing by palladium nanoparticles which is supported on reduced graphene oxide. USE - Method for synthesizing isocoumarines. ADVANTAGE - The method enables to synthesize isocoumarines that has biological properties such as antifungal, cytotoxic, immunomodulatory, antiallergic and anti-tumor.