• 专利标题:   Detecting target molecule with sensor involves immobilizing probe molecules with surface functionalized graphene or surface functionalized carbon nanotubes in sensor channel, and binding target molecules to probe molecules.
  • 专利号:   US2014162375-A1, US9103776-B2
  • 发明人:   AFZALIARDAKANI A, HAN S
  • 专利权人:   INT BUSINESS MACHINES CORP
  • 国际专利分类:   G01N033/543, B82Y010/00, B82Y015/00, B82Y040/00, G01N027/414, G01N033/551, H01L051/00, H01L051/05
  • 专利详细信息:   US2014162375-A1 12 Jun 2014 G01N-033/543 201453 Pages: 9 English
  • 申请详细信息:   US2014162375-A1 US970637 20 Aug 2013
  • 优先权号:   US706784, US970637

▎ 摘  要

NOVELTY - Detecting a target molecule with a sensor device, involves: providing a sensor device comprising a channel and first and second electrodes electrically connected to the channel, where the channel comprises a monolayer of surface functionalized graphene or surface functionalized carbon nanotubes, and the surface functionalized graphene or surface functionalized carbon nanotubes comprise(s) an imidazolidone compound; immobilizing probe molecules with the surface functionalized graphene or surface functionalized carbon nanotubes; and binding target molecules to the probe molecules. USE - The process is useful for detecting a target molecule, preferably streptavidin, with a sensor device, preferably a FET biosensor (all claimed). ADVANTAGE - The method provides a real-time detection of the target molecule in a rapid manner.