▎ 摘　　要

NOVELTY - Preparing chitosan-graphene hollow microcapsules comprises e.g. (i) adding deionized water, absolute ethanol, aqueous ammonia and ethyl orthosilicate, mixing, adding orthosilicate, reacting, filtering, and drying, (ii) adding concentrated sulfuric acid in the flask, placing on ice bath, then adding sodium nitrate and graphite powder, stirring, then adding potassium permanganate, heating, adding deionized water, centrifuging, and freeze-drying, (iii) dispersing silicon dioxide microspheres in water, adding silicon dioxide dispersion into chitosan solution, stirring and post processing. USE - The method is useful for preparing chitosan-graphene hollow microcapsules (claimed). ADVANTAGE - The method has simple operation, produces high yield product; and the product has microsphere size distribution and high quality. DETAILED DESCRIPTION - Preparing chitosan-graphene hollow microcapsules comprises (i) taking 20 ml deionized water, 7 ml absolute ethanol, 2 ml aqueous ammonia and 2 ml ethyl orthosilicate, then adding into a three-necked flask, mixing, adding 25 ml orthosilicate, reacting at 30 degrees C for 6 hours, filtering, washing and drying to obtain silicon dioxide microspheres, (ii) adding 46 ml concentrated sulfuric acid in the flask, placing on ice bath for 3 minutes, then adding 2 g sodium nitrate and 1 g graphite powder, stirring for 30 minutes, then adding 6 g potassium permanganate, heating at 35 degrees C for 30 minutes and stirring for 1 hour, dropwise adding 92 ml deionized water, stirring for 15 minutes, maintaining temperature at 100 degrees C, then adding 150 ml deionized water and 5 ml hydrogen peroxide having concentration of 30 wt.%, centrifuging, washing with 1 mol/l hydrochloric acid solution, then washing the centrifugate with deionized water, adjusting pH of supernatant to 7, and then freeze-drying the centrifuged precipitate to obtain graphene oxide, (iii) dispersing 0.4 g silicon dioxide microspheres in 20 ml water to form dispersion, then adding silicon dioxide dispersion into 50 ml chitosan solution under stirring, stirring the mixture for 4 hours, washing three times with deionized water, then dropwise adding into 50 ml of 2 mg/ml solution of graphene oxide, stirring for 4 hours, and then washing with deionized water for 3 times to obtain chitosan-graphene microspheres, (iv) adding the product obtained in step (iii) into 20 ml a 5 mg/ml genipin aqueous solution, reacting at 37 degrees C for 12 hours, centrifugal washing for 5 times, and then drying to obtain final product, and (v) adding 0.2 g cross-linked chitosan-graphene microspheres into 50 ml of 1% concentration of hydrogen fluoride solution, allowing to stand for 12 hours, centrifugal washing for 4 times to obtain final product.