▎ 摘　　要

NOVELTY - Generating a biopolymer comprises (a) providing many droplets adjacent to a surface, where the droplets comprises a first droplet comprising a first reagent and a second droplet comprising a second reagent, (b) subjecting first droplet and second droplet to motion relative to one another to (i) bring first droplet in contact with second droplet and (ii) form a merged droplet comprising first reagent and second reagent, and (c) using at least (i) first reagent and (ii) second reagent to form at least a portion of biopolymer in the merged droplet, where generating at least portion of biopolymer is performed of less than 10 minutes. USE - The method is useful for generating a biopolymer. ADVANTAGE - The method is economical. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: processing a sample, comprising (a) providing an array comprising: electrodes, and surface configured to support sample, and array is coupled to an electro-mechanical actuator and electro mechanical actuator is configured to vibrate array, (b) introducing droplet to surface, and (c) directing electro-mechanical actuator to apply a frequency of vibration to array; motioning a droplet over an array, comprising electrodes, where no electrode of many electrodes is permanently grounded, and a surface configured to support droplet comprising sample, comprising activating at least a subset of electrodes with a voltage to alter a wetting characteristic of surface, where array does not comprise a permanent reference electrode; ystem for processing a sample, comprising many electrodes, dielectric layer disposed over many electrodes, where the dielectric layer comprises a surface configured to support a droplet comprising sample, and liquid disposed in an interspace adjacent to electrodes and dielectric layer; circularizing a nucleic acid sample, comprising providing a droplet adjacent to an electrowetting array, where the droplet comprises nucleic acid sample, combining droplet with reagent droplets, using electrowetting array to process droplet to circularize nucleic acid sample, and separating droplet from reagent droplets to yield a circularized nucleic acid sample in droplet; and ystem for inducing motion in a droplet, comprising surface configured to support droplet comprising at least one bead formed of a material configured to couple to a magnetic field, actuator coupled a magnet, where magnet is configured to supply magnetic field, the actuator is configured to subject magnetic field to translation along a plane parallel to surface, and a controller operatively coupled to actuator, where controller is configured to direct actuator to subject magnetic field to translation along plane, in which magnetic field translates along plane, and droplet undergoes motion along surface.