• 专利标题:   Composition useful for treating muscle loss disease e.g. muscular dystrophy, comprises polyurethane nanofiber scaffold containing nanographene oxide.
  • 专利号:   KR2022036543-A
  • 发明人:   KIM H, LEE J, LEE H, JO S B, FIVEYEAROLD E, KHANDMAA D, JIN K K, CHA J, KNOWLES J C, ELFIQI A, PATEL K D
  • 专利权人:   UNIV DANKOOK IND ACADEMIC COOP FOUND
  • 国际专利分类:   A61L027/44, A61L027/56
  • 专利详细信息:   KR2022036543-A 23 Mar 2022 A61L-027/56 202231 Pages: 17
  • 申请详细信息:   KR2022036543-A KR118887 16 Sep 2020
  • 优先权号:   KR118887

▎ 摘  要

NOVELTY - The composition comprises nanographene oxide-polyurethane nanofibers scaffold, where the nano-graphene oxide is provided as a polymer structural unit, which comprises anhydrosugar alcohol, polyol and polyisocyanate. The polyol is selected from polycarbonate diol, polycaprolactone diol and polyether polyol, which is obtained by polymerizing the polyol with a vinyl compound. USE - Composition used in composition for treating muscle loss disease. ADVANTAGE - The composition has improved mechanical properties such as hydrophilicity, elasticity and stress relaxation ability, and has soft tissue regeneration effect such as muscle without cytotoxicity, so it is effective in muscle reduction diseases. DESCRIPTION OF DRAWING(S) - The drawing shows the production and physicochemical properties of nanofibers.