• 专利标题:   Multi-analyte biosensing device for detecting markers of acute myocardial infarction, has aqueous solution of graphene quantum dots onto fabricated screen printed carbon electrodes comprising conductive carbon ink and silver ink, anti-cardiac troponin I mix, and anti-C-reactive protein mix.
  • 专利号:   IN202241056157-A
  • 发明人:   JOHN B B R, MUTHAIYAN L, NOEL N
  • 专利权人:   UNIV SASTRA DEEMED
  • 国际专利分类:   B82Y015/00, C09K011/65, G01N027/48, G01N033/68, G01N033/94
  • 专利详细信息:   IN202241056157-A 14 Oct 2022 G01N-033/68 202299 Pages: 19 English
  • 申请详细信息:   IN202241056157-A IN41056157 30 Sep 2022
  • 优先权号:   IN41056157

▎ 摘  要

NOVELTY - The device comprises: 100 μ l of an aqueous solution of graphene quantum dots, the aqueous solution of graphene quantum dots being drop-cast, onto fabricated screen printed carbon electrodes, with: the aqueous solution of graphene quantum dots comprising 2 g citric acid, and a 100 ml solution comprising 10 mg/ml sodium hydroxide solution; and the fabricated screen printed carbon electrodes comprising 0.9 g conductive carbon ink, and 0.5 g silver ink or silver chloride ink; 3 μ l of an anti-cardiac troponin I mix comprising 10 mM of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-hydroxy succinimide; and 3 μ l of an anti-C-reactive protein mix comprising 10 mM of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-hydroxy succinimide. The thickness of electrodeposited graphene quantum dots is 34.75 μ m. USE - The multi-analyte biosensing device is used for simultaneously detecting multiple markers of acute myocardial infarction. ADVANTAGE - The device: facilitates simultaneous detection of anti-cardiac troponin I biomarker and anti-C-reactive protein biomarker; excellent sensing responses; is stable; is repeatable; is simple in construction; and is cost-effective. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method of fabricating a multi-analyte biosensing device, for simultaneously detecting multiple markers of acute myocardial infarction.