• 专利标题:   Method for preparing conductive polymer-based graphene composite porous scaffold, involves dissolving degummed silk in lithium bromide solution followed by centrifuging, filtering and dialyzing to remove impurities and lithium bromide.
  • 专利号:   CN110368532-A
  • 发明人:   ZHANG C, WANG X, ZANG X, HUANG A, CHEN Y, JIN H, LI G
  • 专利权人:   HUAIYIN TECHNOLOGY INST
  • 国际专利分类:   A61L027/44, A61L027/56
  • 专利详细信息:   CN110368532-A 25 Oct 2019 A61L-027/56 201988 Pages: 8 Chinese
  • 申请详细信息:   CN110368532-A CN10543478 21 Jun 2019
  • 优先权号:   CN10543478

▎ 摘  要

NOVELTY - A conductive polymer-based graphene composite porous scaffold preparing method involves dissolving the degummed silk in an aqueous lithium bromide solution, centrifuging, filtering and dialyzing to remove impurities and lithium bromide to obtain an aqueous solution of regenerated silk fibroin and concentrating until the regenerated silk fibroin reaches a certain mass percentage to form a solution. The graphene oxide is ultrasonically dispersed in an aqueous ethanol solution and is referred to as a mixed solution A. The solution is subjected to electro-spinning by using the mixed solution A as a receiving electrode and dried. A regenerated silk fibroin/graphene oxide composite fiber scaffold having a graphene oxide is used as a skin layer and a regenerated silk fibroin is used as a core layer is obtained. The regenerated silk fibroin/graphene oxide composite fiber scaffold is treated by a hydrothermal method and the graphene oxide is reduced and dried to obtain the finished product. USE - Method for preparing conductive polymer-based graphene composite porous scaffold. ADVANTAGE - The method enables preparing conductive polymer-based graphene composite porous scaffold with better conductivity and biocompatibility in simple and cost effective manner.