• 专利标题:   Yellow luminescent graphene quantum dots as nanozymes for neuronal stress suppression, are fabricated from unburnt coal waste.
  • 专利号:   IN202331025091-A
  • 发明人:   DAS S, MANDAL D, KUMAR P, MAL S, DAS T
  • 专利权人:   NAT TECHNOLOGY INST
  • 国际专利分类:   C09K011/65
  • 专利详细信息:   IN202331025091-A 21 Apr 2023 C09K-011/65 202338 English
  • 申请详细信息:   IN202331025091-A IN31025091 01 Apr 2023
  • 优先权号:   IN31025091

▎ 摘  要

NOVELTY - Yellow luminescent graphene quantum dots (YGQDs) are fabricated from unburnt coal waste, and at a concentration of 17.5 millimolar exhibit selective superoxide dismutase (SOD) activity. The yellow luminescent graphene quantum dots at 22 millimolar in lipopolysaccharide (LPS) generated reactive oxygen species (ROS) shows -50% scavenging activity. The yellow luminescent graphene quantum dots show cell survival of 65%,78% and 96% in a dose dependent manner at 6.25 millimolar, 12.5 millimolar and 15 millimolar respectively towards in-vivo induced oxidative stress. The YGQDs retains enzyme mimetic activity for a time span of 5-7 months. USE - Yellow luminescent graphene quantum dots (YGQDs) as nanozymes for neuronal stress suppression. ADVANTAGE - The yellow luminescent graphene quantum dots suggested higher substrate affinity compared SOD, endowing them act SOD mimics viz. degrading the oxygen (O2°) free radicals.