▎ 摘 要
NOVELTY - A sensor device comprises a first layer of graphene providing an interface; and a second layer of at least one bio-compatible component, where the first layer is functionalized by anchoring of the at least one bio-compatible component of the second layer to the first layer. USE - The sensor device is used for detecting analytes and can be applied in diagnostics, testing in industrial samples (quick test for contamination, for resistance), environmental control in healthcare facilities such as hospitals, and in the Biopharma industry such as food production controls. ADVANTAGE - A nanocarbon- or graphene-based device suitable for use as a label-free biosensor is provided. The sensor provides enhanced sensitivity of graphene and combining that with analyte-specific selectivity. The sensors have an advantage in cost and stability when compared with current approaches. Graphene sensors are constructed as thin films which are chemically inert, flexible, bio-compatible, have low noise to electrical read outs and provide multiple parameters. In addition, the mass production of graphene sensors is simplified when compared to mass production of non graphene-based sensors from nano-materials. The sensor is used for label-free, highly selective detection of analytes ranging from gas, liquids, and bio-molecules, and also analyzing cell growth in in vitro culture conditions. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is a method for producing a sensor by providing a first layer of graphene providing an interface; and providing a second layer of at least one bio-compatible component, where the first layer is functionalized by anchoring of the at least one bio-compatible component of the second layer to the first layer.