▎ 摘　　要

NOVELTY - The nucleic acid detection microfluidic chip has a substrate (1) which is provided with a source electrode (11) and a drain electrode (12). A graphene layer (3) is arranged between a first electrode (13) and a second electrode (14). An upper surface of the graphene layer is modified with nano-gold particle. A micro-flow passage plate (2) is covered above the graphene layer. An electrode socket is inserted with a metal wire electrode (241). A micro-flow channel (21) is located between first and second electrodes, and communicated with the graphene layer. USE - Graphene FET-based nucleic acid detection microfluidic chip used for early diagnosis of genetic diseases and cancers. ADVANTAGE - The flexibility of the microfluidic chip is improved. The dosage of the gene sample is effectively reduced. The microfluidic chip occupies small volume. Hence, the microfluidic chip is carried easily. The interference of external environment is avoided, and high sensitivity of the microfluidic chip is achieved. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing graphene FET-based nucleic acid detection microfluidic chip involves preparing graphene electrode slides to copper foil as a substrate. The graphene/copper surface is coated with a layer of polymethyl methacrylate. The copper foil is etched with the ferric chloride solution. The male mold of the micro-flow passage plate is photolithographically on the substrate by soft photolithography, and the polydimethylsiloxane liquid is poured onto the male mold. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic diagram of the nucleic acid detection microfluidic chip. Substrate (1) Micro-flow passage plate (2) Graphene layer (3) Source electrode (11) Drain electrode (12) First electrode (13) Second electrode (14) Micro-flow channel (21) Metal wire electrode (241)